Application of lens backlight digital camera technology in cataract detection

The application of lens backlight digital camera technology in cataract detection Li Jianjun Xu Liang Sun Wei Chen Yingjie Ma Ke relying on the characteristics of the digital image of the lens after illumination in cataract patients. Methods The cataract poster (ataractscreenerrCT-S) was connected to the built-in image acquisition card of the computer. Digital imaging was performed on the lens of 33 normal (64 eyes) normal and cataract patients. The images detected by CT-S digital camera technology were observed. The consistency of the opacity of the lens and the characteristics of the interference factors were observed under a slit lamp microscope. The PhotoShop threshold segmentation method and the self-programmed Matlab program were used to quantitatively analyze the area of ​​lens opacity on CT-S images of different examiners. Results CT-S digital camera technique was used to detect the lens optic and posterior subcapsular opacity in cataract patients. The specificity of CT-S digital camera technique for detecting lens opacity and the sensitivity of cortical and posterior subcapsular cataract were 94% and 90%, respectively. For patients with nuclear cataract, slit lamp microscope is superior to CT-S digital camera. technology. The relative area variation coefficient of lens opacity of CT-S images taken by three different examiners was 2.23%~1086%. CT-S image features: lens cortical opacity is linear, wedge-shaped or clustered with patchy shadows. The posterior subcapsular opacity of the lens is a slab of vacuoles or granules. Conclusion CT-S images have high consistency among examiners. Objectively, the degree of lens cortex and posterior subcapsular opacity can be objectively recorded, which lays a foundation for the quantitative study of cataract, but it is not suitable for the screening and evaluation of nuclear cataract.

The objective and accurate classification, grading and quantitative analysis of cataracts are the basis of cataract prevention. It is especially important to choose good research tools. The methods for evaluating cataract usually include photographs of slit lamp lens and posterior illumination photographs of the skin. ItJ1.2313, 13.9112.78. Normal, human and cataract patients have normal CT-S images; Pattern, without any shadow () s congenital white: in addition to post-polarity and nuclear cataract, some tiny spots or clumpy opacity that is not clinically significant in the periphery of the squamous body can also be displayed (*cortex Type cataract: A non-uniform shadow is visible in the white background of the pupil area, which is consistent with the opacity of the lens cortex, which may be linear, wedge-shaped or clustered in clusters. The color of the shadow is dark and the lens is turbid. The degree of opacity of the lens is lighter than that of the clear shadow. Conversely, the black shadow is usually located in the peripheral part of the lens, and the darkening of the opacity gradually extends toward the central area. When the lens is nearly completely turbid, the entire pupil area is Uneven black shadows (阌丨3,14>, now in different sizes, in vacuo or granular shadows (5.16). Sometimes disc-shaped,

The cataract can exist at the same time. Two images can be obtained through different focal planes. CT-S image detection Cortical and posterior subcutaneous white odor is superior to slit lamp microscope in imaging clarity and crystallographic ffi level. Cut surface image.

Mit congenital 赍 臼 臼 的 的 er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er er A clear yellow-brown nuclear turbidity was observed on the slit lens of the slit lamp, which was more sensitive than CT.S detection (7.18).

Screening for cataracts by ordinary photometry has many shortcomings, such as long time-consuming, costly, photo quality control (such as washing conditions) and data storage is difficult.

To this end, the author has improved this technology, using CT-S digital camera technology to record lens opacity. The results of this study show that CT-S digital camera technology can objectively record the opacity of the lens cortex and posterior capsule, and has important practical value in the investigation of cataract epidemiology and other lens diseases.

The CT-S uses a built-in light-emitting diode to emit a near-infrared transillumination image with a half-width wavelength of 830-870 nm to obtain a post-illumination image of the refractive interstitial. The sensor element of the imaging system is a 1/3-inch monochromatic charge coupled device. Therefore, in theory, as long as the refractive interstitial is turbid, the shadow can be displayed on a transparent background. This instrument focuses on the position of the lens before and after, which lays the foundation for the determination of lens opacity. The focal depth adjustment distance is 24mm, which is beneficial to the identification of the anterior and posterior position of the lens opacity and other refractive interstitial opacity diseases.

Cataract digital imaging technology is one of the new developments in lens research. Compared with the traditional slit lamp inspection, the post-illumination digital image can more objectively record the lens cortex and posterior capsule opacity, and can also more accurately evaluate and measure the degree of lens opacity and its progress. 4. Results of this study It shows that the specificity of CT-S digital camera technology for detecting lens opacity is 94%, and the sensitivity of detecting cortical and posterior subcapsular cataract is 90%, which is similar to the reported results. The coefficient of variation of opacity relative area measurement was 2.23%~10.86%, indicating that CT-S can be used for screening of cataract patients.

The CT-S digital camera system is easy to operate, and the subject can view the lens image by looking at the gaze lamp inside the lens barrel. The observation barrel head can be rotated 360*, so the subject can sit at any position around the instrument for inspection. The examination speed is fast, and the examination time of each patient is about 1 minute, and the qualitative result of the patient's disease can be obtained. The CT-S is very light, only 6.1 kg small, easy to carry, suitable for mobile operations during eye disease epidemiological investigation. In addition, the patient can be directly numbered on the CT-S image to visually distinguish the left and right eye and pupil diameter of the patient.

The results of this study show that the sensitivity of CT-S digital camera technology in the detection of nuclear cataract patients is only 8.33%, far less sensitive than slit lamp inspection, consistent with the reported results abroad, speculation and CT-S imaging principle and Nuclear cataracts are usually associated with uniform turbidity. Therefore, it is better to use a slit lamp imaging method for the evaluation of nuclear cataract.

In addition, CT-S digital camera technology can not completely rule out some interference factors, such as corneal opacity lesions in the pupil area (including corneal cloud, white spots, corneal degeneration, etc.), pterygium, vitreous opacity, eyelashes and eyelid shadows, etc. The impact on the analysis of the results. The opacity and lash shadows on the upper and lower peripheral parts of the lens can be distinguished according to the position of the focus in front of the lens, the shadow activity and the boundary and number of the eyelids. The main points of identification of opacity with other refractive interstitial are the orientation, density, shape, focus position and shadow of the shadow. It is fluttering with the rotation of the eyeball. For example, when the vitreous is turbid, the focus position is behind the lens and the shadow is fluttering. The pterygium can also have triangular or wedge-shaped shadows on the CT-S image, but is usually located on the nasal side, with neovascularization visible on the surface and low density infiltrates before the shadow.

When quantitatively analyzing CT-S images, there are some differences in the images taken by different examiners. For the same subject, the pupil size, the brightness level of the CT-S, and the threshold adjustment of the PhotoShop software used were consistent. Therefore, the quantitative difference is caused by the nuances of the focus plane of different examiners when taking CT-S images. The opacity of the lens is stereoscopic, and it is generally required to take one image before and after the lens, but the error cannot be completely controlled. The results of this study showed that the coefficient of variation of the posterior subcapsular opacity area (2.23%) in different examiner images was smaller than cortical opacity (8.33%~10.86%), which was related to the relative concentration of posterior subcapsular opacity and the smaller range. .

CT-S digital camera technology can be used not only for the degree and type of lens opacity in patients with asymptomatic and non-symptomatic cataracts in epidemiological studies, but also for the prevalence and incidence of cataract. Rate and incidence of risk factors. In addition, in clinical practice, CT-S digital camera technology can also be used to track the progress of patients with lens cortex and posterior subcapsular opacity, predict its clinical course and prognosis, and measure the actual response and therapeutic effect of cataract treatment on lens opacity. To evaluate the surgical outcomes of cataract patients, especially the postoperative cataract after intraocular lens surgery and the location of the intraocular lens. Posterior cataract is an urgent problem in cataract research. CT-S digital camera technology has opened up a new objective evaluation method. In short, CT-S digital camera technology can be applied to cataract epidemiology research, clinical cataract case control research and cohort observation, is a simple and objective cataract research tool.

(:002-04-16) (Editor: Cai Lifeng, Yang Qingqing)

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